Endocrine Abstracts

This 65 years old lady, who had undergone neck explorations for parathyroid adenoma in 1972 and 2000, presented with vomiting, lethargy, muscle weakness and polyuria. On admission, her serum Calcium was 2.98 mmol/l (2.18-2.63) with elevated parathyroid hormone of 151 pg/ml (10-70). A Thallium-Technetium parathyroid scan was normal but Octreotide scan showed an area of uptake in the superior mediastinum. A MIBI scan followed, which was unhelpful as were ultrasound scan of the n...

Patients who have Sr. Prolactin level >3000 mU/l (n=24) were selected from the Biochemistry laboratory record & patients with confirmed diagnosis of prolactinoma (n=33) identified and / followed up at Endocrine Clinic between December 1999 and October 2001 were studied. The mean age of the patients were 45.03+ 14.09 years and 72% were women. Of the patients diagnosed to have prolactinoma, 16 had microprolactinoma. 16 had macroprolactinoma and 1 had stalk disconnection. ...

A 49 year old man presented in 1998 with marked visual disturbance. MRI scan revealed a very large pituitary tumour with compression of the anterior optic pathways. Prolactin was markedly elevated at 259,000 milliunits per litre confirming the diagnosis of a giant prolactinoma. A trial of dopamine agonist therapy did not result in any improvement in vision and he proceeded to pituitary surgery. Vision improved and prolactin levels were suppressed by dopamine agonist therapy wi...

Hyperthyroidism has a profound effect on the cardiovascular system. Heart failure is common in the elderly patients with hyperthyroidism who have co-existing cardiac disease.We report a case of severe heart failure in a 43-year-old woman with Graves' disease. She presented with cough and breathlessness for 3 weeks. There was a strong family history of thyroid disease. On presentation, she had florid hyperthyroidism with features of Graves' disease. Exam...